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Technology
Next Generation Sequencing
Next Generation Sequencing (NGS) is a multifaceted technology that enables high-throughput analysis of DNA, RNA, epigenetic patterns, and even proteomics. Employing both short-read and long-read methodologies, it leverages computational algorithms to achieve scalability, speed, and precision. NGS is widely applied in academic research, drug development, diagnostics, and consumer genomics.
Clinical Enterprise is a leading provider of NGS services, utilizing Illumina platforms to deliver cutting-edge sequencing and bioinformatics solutions to our customers. In an effort to power collaboration, and guided by a group of highly credentialed scientists, Clinical Enterprise provides end-to-end services including experimental design and feasibility, sample extraction, library preparation, sequencing, and data delivery. Our standard and custom NGS assays have been validated according to CAP/CLIA regulations, either RUO or LDT grade, and across multiple partnerships with academic, biopharma, consumer genomics, and clinical institutions.
OpenArray & qPCR
OpenArray™ technology is a real-time PCR-based solution designed for high-throughput and cost-effective qPCR applications. This innovative workflow employs a slide-sized chip embedded with thousands of nanowells, optimizing reagent utilization and increasing sample throughput. The system offers scalability, allowing for the adjustment of either the number of samples per chip or the variety of array targets. Clinical Enterprise currently supplies several customized OpenArray panels to its clients, ensuring both budget-friendly and quality-driven results.
Offering highly sensitive and reliable detection for known variants of interest, qPCR can provide rapid, cost-effective genotyping results for any number of samples. qPCR genotyping is an ideal option when screening or quantifying a smaller numbers of targets (<= 20). Applications are wide-ranging, with qPCR predominantly used in clinical diagnostics, genetic research, infectious studies, SNP analysis, and more. Clinical Enterprise provides several custom single and multiplex qPCR assays, ideal for rapid, high-quality results.
Microarray
Utilizing cutting-edge Illumina Infinium array technology, microarrays can economically perform targeted, exome-wide, and genome-wide studies. Whether the application is just a small number of targets or thousands, microarrays provide a flexible option to gain valuable insight into clinical and research applications. From discovery applications to routine screening, microarrays are a valuable tool for variant detection. Research applications include GWAS, cytogenetics, pharmacogenetics, methylation, and drug discovery. Clinical Enterprise offers reliable, automated workflows for several microarray options and delivers high-quality data and fast turnaround.
Custom Solutions
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Clinical Enterprise aspires to meet our clients’ diverse needs. Together with a highly-credential development team and robust automated instrument platforms, we can develop new assays and design custom workflows to meet your unique testing needs.
Clinical Enterprise can support your most ambitious projects with a tailored project management and data delivery framework to meet your exact objectives. Our development and project management team can bring success to any project with hands-on, technical project design, deadline-driven project execution, customizable data delivery or integration, and qualified technical support to the customer.