Instruments

Liquid Handling

Hamilton STAR Systems

• Full instrument fleet capable of >10,000 extractions in a single shift
• Each instrument has most extensive Hamilton configuration with heater/shaker, 16 individual channels, and 96 well head
• Single instrument can perform DNA/RNA purification on 384 samples in 2.5 hours

Agilent BRAVO Systems

• Transfers four 96-well plates to 384-well in under 5 minutes
• Highly flexible configurations for library prep automation
• Single instrument capable of setting up >50 384-well PCR plates in a shift
• Small footprint

Thermo Fisher KingFisher 96 Flex Systems

• Extremely fast and efficient—up to 1,000 extractions per day
• Compatible with multiple assay types, including RNA and DNA extraction; bisulfite conversion for methylation
• Consistent and reliable results
• Small footprint

TECAN System for Arrays

• Increases microarray genotyping capacity 6X from 288 samples/week to >1,700
• Reduces direct labor time of array wet bench work by nearly 75%
• Performs wet bench steps for EPIC, GDA, GSA, and Omni microarray format
• Improves results consistency and reduces risk of laboratory errors

qPCR Systems

QuantStudio 5

• Capacity for >20,000 genotyping reactions per day using 384-well format
• 384-well real time PCR Systems
• Optimized for TaqMan genotyping, expression assays, and CNV analysis for a wide range of applications

QuantStudio12K Flex with OpenArray Technology

• Between 432 (256 targets) and 5,000 (16 targets) samples per day, depending on panel
• SNP genotyping, gene expression, CNV analysis, miRNA analysis
• Prebuild or customize configurations to offer as few as 16 targets and 144 samples/plate or 256 targets and 12 samples/plate

Sequencers and Analyzers

NovaSeq X Plus

• Scalability to provide anywhere from 4 to 64 human genome samples per flow cell
• Next-level sequencing output with as much as 16TB of data produced per run
• Whole Genome Sequencing and Whole Exome Sequencing at flexible coverage levels to meet custom requirements for any project

NovaSeq 6000

• Flexibility to run up to eight different sequencing assays simultaneously
• Sequencing output with as much as 5TB of data produced per run
• Whole Genome Sequencing and Whole Exome Sequencing at flexible coverage levels to meet custom requirements for any project

Illumina MiSeqs

• Up to 2,500 16S samples per week capacity
• Ability to run four separate assay types simultaneously
• Used for targeted sequencing, microbiome, custom sequencing projects
• Each system is integrated with BaseSpace and Clinical Enterprise NAS system for automatic data export

Illumina NextSeq 500

• High throughput instrument used for larger targeted panels, WES, and metagenomics
• Good alternative to MiSeq for applications requiring deeper coverage and read counts
• Cost effective option due to flexibility to perform mid and high output sequencing configurations

Illumina iSCAN for microarrays

• Can scan up to 24 BeadChips in one day (576 samples)
• Short analysis time means one instrument can absorb significant throughput
• System is integrated with BaseSpace and Clinical Enterprise NAS system for automatic data export
• Scans all Illumina BeadChips

Applied Biosystems™ 3730xl DNA Analyzer for Sanger Sequencing

• Sequence capacity of 16 sample plates (96-well or 384-well) provides high-quality, high-throughput sequencing for less
• On-board reagent handling delivers up to 48 hours of continuous operation
• Performs a wide variety of applications including resequencing, SNP screening, SNP validation, and more
• Integrated data analysis tools reduce time-to-results for genotyping and resequencing