Skip to main content

Services

Explore Clinical Enterprise Services

Sequencing Services

Whole Genome Sequencing (WGS)

Established to deliver a comprehensive view of the entire genome, whole genome sequencing (WGS) is a powerful method used in discovery applications. WGS provides a detailed genome view, base-by-base, driving advances in genomics research across academic, clinical, consumer, and biopharma industries. WGS can reveal both large and small genetic variants, key in determining inherited disorders, characterizing mutations, and tracking disease outbreaks.

Explore WGS Services
Whole Transcriptome Sequencing (WTS)

Designed to offer an extensive view of RNA transcripts, whole transcriptome sequencing (WTS) is a vital tool for gene expression analysis and discovery applications. WTS delivers a comprehensive and precise profile of gene activity, capturing both coding and non-coding RNA sequences, driving advancements in transcriptomics research. WTS can identify differentially expressed genes, splice variants, and novel transcripts, crucial for understanding gene regulation, disease mechanisms, and developing targeted therapies.

Explore WTS Services
Whole Exome Sequencing (WES)

Optimized to capture the exonic regions of >20,000 human genes, whole exome sequencing (WES) examines the genetic etiology of many different conditions. WES adds valuable insight to both academic and clinical research; it is most often a tool to help diagnose patients who present with complex biochemical and clinical symptoms, birth defects, and developmental delay.

16S Sequencing

Target specific regions of the bacterial 16S rRNA gene to identify and understand the abundance of various microbial communities. Diverse research applications include classifying beneficial bacteria and pathogens and comparative analysis of healthy and diseased groups. Clinical Enterprise offers 16S microbial profiling of variable regions of the 16S rRNA gene with flexible requirements or configurations around read counts and required depth of sequencing.

Shotgun Metagenomics

Rather than isolating only specific amplicon regions, shotgun metagenomics sequences all genomic DNA present in a sample, including both host and microorganisms. While 16S NGS profiling provides a snapshot of the microbial community, shotgun metagenomics gives insight into the taxonomic profile and abundances, and also functional predictions, gut-host relationships, drug discovery data, [RL4] and more precise understanding of specific microbial strains.

Targeted Resequencing

This sequencing technique allows for deep coverage of specific genomic loci of interest to identify common and rare variants that may be associated with a specific genetic condition or trait. Using capture-based probes, Clinical Enterprise can work with you to design and optimize a custom assay that suits any application. In addition, Clinical Enterprise offers a fully LDT validated clinical assay called LipidSeq, which targets 23 genes associated with rare lipid and lipoprotein disorders.

Genotyping Services

qPCR & OpenArray Genotyping

Offering highly sensitive and reliable detection for known variants of interest, qPCR can provide rapid, cost-effective genotyping results for any number of samples. qPCR genotyping is an ideal option when screening or quantifying a smaller numbers of targets (<= 20).

Similarly, OpenArray™ is a real-time PCR-based solution designed for high-throughput and cost-effective qPCR applications. This innovative workflow employs a slide-sized chip embedded with thousands of nanowells, optimizing reagent utilization and increasing sample throughput. The system offers scalability, allowing for the adjustment of either the number of samples per chip or the variety of array targets.

Applications are wide-ranging, with OpenArray and qPCR predominantly used in clinical diagnostics, genetic research, infectious studies, SNP analysis, and more. Clinical Enterprise provides several custom OpenArray and qPCR panels to several of its clients, ideal for rapid, budget-friendly, high-quality results.

Microarray Services

Infinium Microarrays

Utilizing cutting-edge Illumina Infinium array technology, microarrays can economically perform targeted, exome-wide, and genome-wide studies. Whether the application is just a small number of targets or thousands, microarrays provide a flexible option to gain valuable insight into clinical and research applications. Research applications include GWAS, cytogenetics, pharmacogenetics, methylation, and drug discovery. Clinical Enterprise offers reliable, automated workflows for several microarray options and delivers high-quality data and fast turnaround.

Extraction and Preparation

Extraction and Preparation

Quality lab testing begins with efficient and cost-effective sample preparation. With our fleet of automated equipment, Clinical Enterprise provides efficient extraction and preparation at several scales, suitable for all levels of throughput needs across a wide variety of samples. Clinical Enterprise can provide quality control using fluorometric or gel electrophoresis, depending on the specific requirements.

Custom Services

Custom Services

Clinical Enterprise aspires to meet our clients’ diverse needs. Together with a highly-credential development team and robust automated instrument platforms, we can develop new assays and design custom workflows to meet your unique testing needs.

Clinical Enterprise can support your most ambitious projects with a tailored project management and data delivery framework to meet your exact objectives. Our development and project management team can bring success to any project with hands-on, technical project design, deadline-driven project execution, customizable data delivery or integration, and qualified technical support to the customer.

Ready to move your work forward?

Contact us

Tell us about your specific technical needs and provide your availability. We will reach out and schedule an introductory meeting with our business development team.

Meet with us

During our meeting, we will detail our capabilities and get to understand your needs further to ensure a partnership with Clinical Enterprise is the right fit.

Work with us

After our meeting, our business development team will send a detailed quote and contract containing the written specifications of your needs and our partnership.
Skip to content