Services

Established to deliver a comprehensive view of the entire genome, whole genome sequencing (WGS) is a powerful method used in discovery applications. WGS provides a detailed genome view, base-by-base, driving advances in genomics research across academic, clinical, consumer, and biopharma industries. WGS can reveal both large and small genetic variants, key in determining inherited disorders, characterizing mutations, and tracking disease outbreaks.

Designed to offer an extensive view of RNA transcripts, whole transcriptome sequencing (WTS) is a vital tool for gene expression analysis and discovery applications. WTS delivers a comprehensive and precise profile of gene activity, capturing both coding and non-coding RNA sequences, driving advancements in transcriptomics research. WTS can identify differentially expressed genes, splice variants, and novel transcripts, crucial for understanding gene regulation, disease mechanisms, and developing targeted therapies.

Optimized to capture the exonic regions of >20,000 human genes, whole exome sequencing (WES) examines the genetic etiology of many different conditions. WES adds valuable insight to both academic and clinical research; it is most often a tool to help diagnose patients who present with complex biochemical and clinical symptoms, birth defects, and developmental delay.

Target specific regions of the bacterial 16S rRNA gene to identify and understand the abundance of various microbial communities. Diverse research applications include classifying beneficial bacteria and pathogens and comparative analysis of healthy and diseased groups. Clinical Enterprise offers 16S microbial profiling of variable regions of the 16S rRNA gene with flexible requirements or configurations around read counts and required depth of sequencing.

Rather than isolating only specific amplicon regions, shotgun metagenomics sequences all genomic DNA present in a sample, including both host and microorganisms. While 16S NGS profiling provides a snapshot of the microbial community, shotgun metagenomics gives insight into the taxonomic profile and abundances, and also functional predictions, gut-host relationships, drug discovery data, [RL4] and more precise understanding of specific microbial strains.

Utilizing cutting-edge Illumina Infinium array technology, microarrays can economically perform targeted, exome-wide, and genome-wide studies. Whether the application is just a small number of targets or thousands, microarrays provide a flexible option to gain valuable insight into clinical and research applications. Research applications include GWAS, cytogenetics, pharmacogenetics, methylation, and drug discovery. Clinical Enterprise offers reliable, automated workflows for several microarray options and delivers high-quality data and fast turnaround.